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|Section2= |Section3= }} 3-Quinuclidinyl benzilate (QNB) — IUPAC name 1-azabicyclo()oct-3-yl 2-hydroxy-2,2-diphenylacetate; US Army code EA-2277; NATO code BZ; Soviet code Substance 78 — is an odorless military incapacitating agent.〔QNB: Incapacitating Agent. (Emergency Response Safety and Health Database ). National Institute for Occupational Safety and Health. Accessed April 20, 2009.〕 BZ is a glycolate anticholinergic compound related to atropine, scopolamine, hyoscyamine, and other deliriants. Dispersal would be as an aerosolized solid (primarily for inhalation) or as agent dissolved in one or more solvents for ingestion or percutaneous absorption. Acting as a competitive inhibitor of acetylcholine at postsynaptic and postjunctional muscarinic receptor sites in smooth muscle, exocrine glands, autonomic ganglia, and the brain, BZ decreases the effective concentration of acetylcholine seen by receptors at these sites. Thus, BZ causes PNS effects that in general are the opposite of those seen in nerve agent poisoning. CNS effects include stupor, confusion, and confabulation with concrete and panoramic illusions and hallucinations, and with regression to primitive, involuntary behaviors such as floccillation and disrobing. Physostigmine, which increases the concentration of acetylcholine in synapses and in neuromuscular and neuroglandular junctions, is a specific antidote. Production of BZ is controlled under schedule 2 of the Chemical Weapons Convention of 1997. ==History== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「3-Quinuclidinyl benzilate」の詳細全文を読む スポンサード リンク
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